microRNA125对无义突变的人凝血因子Ⅸ基因调控的分子机制

OBJECTIVE: To construct human coagulation factor Ⅸ mini-gene (Mini-hF9) and some nonsense mutants, detect the levels of the Mini-hF9 mRNA, and analyze the molecular mechanism of microRNA125 regulating F9 gene with nonsense mutation. METHODS: Three nonsense mutants were obtained by using PCR mutagene...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial office of Chinese Journal of Hematology 2016
Materias:
论著
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348302/
https://www.ncbi.nlm.nih.gov/pubmed/27210873
http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2016.05.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348302/
https://www.ncbi.nlm.nih.gov/pubmed/27210873
http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2016.05.007

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