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靶向抑制miRNA-21对K562细胞增殖及PTEN-PI3K/AKT通路的影响
OBJECTIVE: To investigate the K562 cells biological function and related molecular changes in PTEN-PI3K/AKT signaling pathway of leukemia K562 cells by inhibiting the miRNA-21 expression to explore its pathogenesis of leukemia. METHODS: The chemical synthetic miRNA-21 inhibitor was transfered into K...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
Editorial office of Chinese Journal of Hematology
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348512/ https://www.ncbi.nlm.nih.gov/pubmed/27995885 http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2016.11.011 |