Cargando…

Induction of the Endoplasmic-Reticulum-Stress Response: MicroRNA-34a Targeting of the IRE1α-Branch

Neurodegenerative disorders such as Alzheimer’s disease (AD) and Parkinson’s disease (PD) are characterized by the accumulation of misfolded proteins in the endoplasmic reticulum (ER) and the unfolded protein response (UPR). Modulating the UPR is one of the major challenges to counteract the develop...

Descripción completa

Detalles Bibliográficos
Autores principales: Krammes, Lena, Hart, Martin, Rheinheimer, Stefanie, Diener, Caroline, Menegatti, Jennifer, Grässer, Friedrich, Keller, Andreas, Meese, Eckart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348704/
https://www.ncbi.nlm.nih.gov/pubmed/32531952
http://dx.doi.org/10.3390/cells9061442