Cargando…

Orthotopic T-Cell Receptor Replacement—An “Enabler” for TCR-Based Therapies

Natural adaptive immunity co-evolved with pathogens over millions of years, and adoptive transfer of non-engineered T cells to fight infections or cancer so far exhibits an exceptionally safe and functional therapeutic profile in clinical trials. However, the personalized nature of therapies using v...

Descripción completa

Detalles Bibliográficos
Autores principales: Schober, Kilian, Müller, Thomas R., Busch, Dirk H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348731/
https://www.ncbi.nlm.nih.gov/pubmed/32492858
http://dx.doi.org/10.3390/cells9061367