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Orthotopic T-Cell Receptor Replacement—An “Enabler” for TCR-Based Therapies
Natural adaptive immunity co-evolved with pathogens over millions of years, and adoptive transfer of non-engineered T cells to fight infections or cancer so far exhibits an exceptionally safe and functional therapeutic profile in clinical trials. However, the personalized nature of therapies using v...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348731/ https://www.ncbi.nlm.nih.gov/pubmed/32492858 http://dx.doi.org/10.3390/cells9061367 |