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Orthotopic T-Cell Receptor Replacement—An “Enabler” for TCR-Based Therapies

Natural adaptive immunity co-evolved with pathogens over millions of years, and adoptive transfer of non-engineered T cells to fight infections or cancer so far exhibits an exceptionally safe and functional therapeutic profile in clinical trials. However, the personalized nature of therapies using v...

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Detalles Bibliográficos
Autores principales:	Schober, Kilian, Müller, Thomas R., Busch, Dirk H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348731/ https://www.ncbi.nlm.nih.gov/pubmed/32492858 http://dx.doi.org/10.3390/cells9061367

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