Nucleophosmin 1 Mutations in Acute Myeloid Leukemia

Nucleophosmin (NPM1) is a ubiquitously expressed nucleolar protein involved in ribosome biogenesis, the maintenance of genomic integrity and the regulation of the ARF-p53 tumor-suppressor pathway among multiple other functions. Mutations in the corresponding gene cause a cytoplasmic dislocation of t...

Descripción completa

Detalles Bibliográficos
Autores principales: Zarka, Jabra, Short, Nicholas J., Kanagal-Shamanna, Rashmi, Issa, Ghayas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348733/
https://www.ncbi.nlm.nih.gov/pubmed/32545659
http://dx.doi.org/10.3390/genes11060649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348733/
https://www.ncbi.nlm.nih.gov/pubmed/32545659
http://dx.doi.org/10.3390/genes11060649

Ejemplares similares