Isoleucine 44 Hydrophobic Patch Controls Toxicity of Unanchored, Linear Ubiquitin Chains through NF-κB Signaling

Ubiquitination is a post-translational modification that regulates cellular processes by altering the interactions of proteins to which ubiquitin, a small protein adduct, is conjugated. Ubiquitination yields various products, including mono- and poly-ubiquitinated substrates, as well as unanchored p...

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Detalles Bibliográficos
Autores principales: Blount, Jessica R., Libohova, Kozeta, Silva, Gustavo M., Todi, Sokol V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348737/
https://www.ncbi.nlm.nih.gov/pubmed/32580388
http://dx.doi.org/10.3390/cells9061519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348737/
https://www.ncbi.nlm.nih.gov/pubmed/32580388
http://dx.doi.org/10.3390/cells9061519

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