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Altered Transcription Factor Binding and Gene Bivalency in Islets of Intrauterine Growth Retarded Rats

Intrauterine growth retardation (IUGR), which induces epigenetic modifications and permanent changes in gene expression, has been associated with the development of type 2 diabetes. Using a rat model of IUGR, we performed ChIP-Seq to identify and map genome-wide histone modifications and gene dysreg...

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Detalles Bibliográficos
Autores principales: Lien, Yu-Chin, Wang, Paul Zhiping, Lu, Xueqing Maggie, Simmons, Rebecca A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348746/
https://www.ncbi.nlm.nih.gov/pubmed/32527043
http://dx.doi.org/10.3390/cells9061435