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Altered Transcription Factor Binding and Gene Bivalency in Islets of Intrauterine Growth Retarded Rats
Intrauterine growth retardation (IUGR), which induces epigenetic modifications and permanent changes in gene expression, has been associated with the development of type 2 diabetes. Using a rat model of IUGR, we performed ChIP-Seq to identify and map genome-wide histone modifications and gene dysreg...
Autores principales: | Lien, Yu-Chin, Wang, Paul Zhiping, Lu, Xueqing Maggie, Simmons, Rebecca A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348746/ https://www.ncbi.nlm.nih.gov/pubmed/32527043 http://dx.doi.org/10.3390/cells9061435 |
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