Huntington’s Disease—An Outlook on the Interplay of the HTT Protein, Microtubules and Actin Cytoskeletal Components

Huntington’s disease is a severe and currently incurable neurodegenerative disease. An autosomal dominant mutation in the Huntingtin gene (HTT) causes an increase in the polyglutamine fragment length at the protein N-terminus. The consequence of the mutation is the death of neurons, mostly striatal...

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Detalles Bibliográficos
Autores principales: Taran, Aleksandra S., Shuvalova, Lilia D., Lagarkova, Maria A., Alieva, Irina B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348758/
https://www.ncbi.nlm.nih.gov/pubmed/32580314
http://dx.doi.org/10.3390/cells9061514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348758/
https://www.ncbi.nlm.nih.gov/pubmed/32580314
http://dx.doi.org/10.3390/cells9061514

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