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A Cellular Automaton Model as a First Model-Based Assessment of Interacting Mechanisms for Insulin Granule Transport in Beta Cells

In this paper a first model is derived and applied which describes the transport of insulin granules through the cell interior and at the membrane of a beta cell. A special role is assigned to the actin network, which significantly influences the transport. For this purpose, microscopically measured...

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Detalles Bibliográficos
Autores principales: Müller, Michael, Glombek, Mathias, Powitz, Jeldrick, Brüning, Dennis, Rustenbeck, Ingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348896/
https://www.ncbi.nlm.nih.gov/pubmed/32570905
http://dx.doi.org/10.3390/cells9061487