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Intrinsic Abnormalities of Cystic Fibrosis Airway Connective Tissue Revealed by an In Vitro 3D Stromal Model

Cystic fibrosis is characterized by lung dysfunction involving mucus hypersecretion, bacterial infections, and inflammatory response. Inflammation triggers pro-fibrotic signals that compromise lung structure and function. At present, several in vitro cystic fibrosis models have been developed to stu...

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Detalles Bibliográficos
Autores principales: Mazio, Claudia, Scognamiglio, Laura S., De Cegli, Rossella, Galietta, Luis J. V., Di Bernardo, Diego, Casale, Costantino, Urciuolo, Francesco, Imparato, Giorgia, Netti, Paolo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348935/
https://www.ncbi.nlm.nih.gov/pubmed/32492951
http://dx.doi.org/10.3390/cells9061371