DNA Hypermethylation and Unstable Repeat Diseases: A Paradigm of Transcriptional Silencing to Decipher the Basis of Pathogenic Mechanisms

Unstable repeat disorders comprise a variable group of incurable human neurological and neuromuscular diseases caused by an increase in the copy number of tandem repeats located in various regions of their resident genes. It has become clear that dense DNA methylation in hyperexpanded non-coding rep...

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Detalles Bibliográficos
Autores principales: Poeta, Loredana, Drongitis, Denise, Verrillo, Lucia, Miano, Maria Giuseppina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348995/
https://www.ncbi.nlm.nih.gov/pubmed/32580525
http://dx.doi.org/10.3390/genes11060684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348995/
https://www.ncbi.nlm.nih.gov/pubmed/32580525
http://dx.doi.org/10.3390/genes11060684

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