Association of NUDT15 c.415C>T and FPGS 2572C>T Variants with the Risk of Early Hematologic Toxicity During 6-MP and Low-Dose Methotrexate-Based Maintenance Therapy in Indian Patients with Acute Lymphoblastic Leukemia

Genetic variants influencing the pharmacokinetics and/or pharmacodynamics of the chemotherapeutic drugs used in Acute Lymphoblastic Leukemia (ALL) therapy often contribute to the occurrence of treatment related toxicity (TRT). In this study, we explored the association of candidate genetic variants...

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Detalles Bibliográficos
Autores principales: Kodidela, Sunitha, Dorababu, Patchava, Thakkar, Dimpal N., Dubashi, Biswajit, Sundaram, Rajan, Muralidharan, Niveditha, Nidanapu, Ravi Prasad, Aribandi, Anil, Pradhan, Suresh Chandra, Uppugunduri, Chakradhara Rao Satyanarayana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349017/
https://www.ncbi.nlm.nih.gov/pubmed/32481505
http://dx.doi.org/10.3390/genes11060594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349017/
https://www.ncbi.nlm.nih.gov/pubmed/32481505
http://dx.doi.org/10.3390/genes11060594

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