A Prime-Boost Immunization Strategy with Vaccinia Virus Expressing Novel gp120 Envelope Glycoprotein from a CRF02_AG Isolate Elicits Cross-Clade Tier 2 HIV-1 Neutralizing Antibodies

Development of new immunogens eliciting broadly neutralizing antibodies (bNAbs) is a main priority for the HIV-1 vaccine field. Envelope glycoproteins from non-B-non-C HIV-1clades have not been fully explored as components of a vaccine. We produced Vaccinia viruses expressing a truncated version of...

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Detalles Bibliográficos
Autores principales: Calado, Rita, Duarte, Joana, Borrego, Pedro, Marcelino, José Maria, Bártolo, Inês, Martin, Francisco, Figueiredo, Inês, Almeida, Silvia, Graça, Luís, Vítor, Jorge, Aires da Silva, Frederico, Dias, Inês, Carrapiço, Belmira, Taveira, Nuno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349027/
https://www.ncbi.nlm.nih.gov/pubmed/32272637
http://dx.doi.org/10.3390/vaccines8020171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349027/
https://www.ncbi.nlm.nih.gov/pubmed/32272637
http://dx.doi.org/10.3390/vaccines8020171

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