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The S1P–S1PR Axis in Neurological Disorders—Insights into Current and Future Therapeutic Perspectives
Sphingosine 1-phosphate (S1P), derived from membrane sphingolipids, is a pleiotropic bioactive lipid mediator capable of evoking complex immune phenomena. Studies have highlighted its importance regarding intracellular signaling cascades as well as membrane-bound S1P receptor (S1PR) engagement in va...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349054/ https://www.ncbi.nlm.nih.gov/pubmed/32580348 http://dx.doi.org/10.3390/cells9061515 |