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The S1P–S1PR Axis in Neurological Disorders—Insights into Current and Future Therapeutic Perspectives

Sphingosine 1-phosphate (S1P), derived from membrane sphingolipids, is a pleiotropic bioactive lipid mediator capable of evoking complex immune phenomena. Studies have highlighted its importance regarding intracellular signaling cascades as well as membrane-bound S1P receptor (S1PR) engagement in va...

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Detalles Bibliográficos
Autores principales:	Lucaciu, Alexandra, Brunkhorst, Robert, Pfeilschifter, Josef M., Pfeilschifter, Waltraud, Subburayalu, Julien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349054/ https://www.ncbi.nlm.nih.gov/pubmed/32580348 http://dx.doi.org/10.3390/cells9061515

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