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Elements of the Endomucin Extracellular Domain Essential for VEGF-Induced VEGFR2 Activity

Endomucin (EMCN) is the type I transmembrane glycoprotein, mucin-like component of the endothelial cell glycocalyx. We have previously shown that EMCN is necessary for vascular endothelial growth factor (VEGF)-induced VEGF receptor 2 (VEGFR2) internalization and downstream signaling. To explore the...

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Detalles Bibliográficos
Autores principales: Hu, Zhengping, Cano, Issahy, Saez-Torres, Kahira L., LeBlanc, Michelle E., Saint-Geniez, Magali, Ng, Yin-Shan, Argüeso, Pablo, D’Amore, Patricia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349057/
https://www.ncbi.nlm.nih.gov/pubmed/32517158
http://dx.doi.org/10.3390/cells9061413