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Identification of Prion Disease-Related Somatic Mutations in the Prion Protein Gene (PRNP) in Cancer Patients

Prion diseases are caused by misfolded prion protein (PrP(Sc)) and are accompanied by spongiform vacuolation of brain lesions. Approximately three centuries have passed since prion diseases were first discovered around the world; however, the exact role of certain factors affecting the causative age...

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Detalles Bibliográficos
Autores principales: Kim, Yong-Chan, Won, Sae-Young, Jeong, Byung-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349074/
https://www.ncbi.nlm.nih.gov/pubmed/32560489
http://dx.doi.org/10.3390/cells9061480