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Metabolomic Profiling of Plasma and Erythrocytes in Sickle Mice Points to Altered Nociceptive Pathways

Few data-driven metabolomic approaches have been reported in sickle cell disease (SCD) to date. We performed a metabo-lipidomic study on the plasma and red blood cells of a steady-state mouse model carrying the homozygous human hemoglobin SS, compared with AS and AA genotypes. Among the 188 metaboli...

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Detalles Bibliográficos
Autores principales: Dembélé, Klétigui Casimir, Mintz, Thomas, Veyrat-Durebex, Charlotte, Chabrun, Floris, Chupin, Stéphanie, Tessier, Lydie, Simard, Gilles, Henrion, Daniel, Mirebeau-Prunier, Delphine, Chao de la Barca, Juan Manuel, Tharaux, Pierre-Louis, Reynier, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349104/
https://www.ncbi.nlm.nih.gov/pubmed/32466566
http://dx.doi.org/10.3390/cells9061334