Newcastle Disease Virus (NDV) Oncolytic Activity in Human Glioma Tumors Is Dependent on CDKN2A-Type I IFN Gene Cluster Codeletion

Glioblastoma (GBM) is the most aggressive and frequent primary brain tumor in adults with a median overall survival of 15 months. Tumor recurrence and poor prognosis are related to cancer stem cells (CSCs), which drive resistance to therapies. A common characteristic in GBM is CDKN2A gene loss, loca...

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Detalles Bibliográficos
Autores principales: García-Romero, Noemi, Palacín-Aliana, Irina, Esteban-Rubio, Susana, Madurga, Rodrigo, Rius-Rocabert, Sergio, Carrión-Navarro, Josefa, Presa, Jesús, Cuadrado-Castano, Sara, Sánchez-Gómez, Pilar, García-Sastre, Adolfo, Nistal-Villan, Estanislao, Ayuso-Sacido, Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349162/
https://www.ncbi.nlm.nih.gov/pubmed/32516884
http://dx.doi.org/10.3390/cells9061405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349162/
https://www.ncbi.nlm.nih.gov/pubmed/32516884
http://dx.doi.org/10.3390/cells9061405

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