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Computational Model Reveals a Stochastic Mechanism behind Germinal Center Clonal Bursts
Germinal centers (GCs) are specialized compartments within the secondary lymphoid organs where B cells proliferate, differentiate, and mutate their antibody genes in response to the presence of foreign antigens. Through the GC lifespan, interclonal competition between B cells leads to increased affi...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349200/ https://www.ncbi.nlm.nih.gov/pubmed/32532145 http://dx.doi.org/10.3390/cells9061448 |