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Novel Brown Coat Color (Cocoa) in French Bulldogs Results from a Nonsense Variant in HPS3

Brown or chocolate coat color in many mammalian species is frequently due to variants at the B locus or TYRP1 gene. In dogs, five different TYRP1 loss-of-function alleles have been described, which explain the vast majority of dogs with brown coat color. Recently, breeders and genetic testing labora...

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Detalles Bibliográficos
Autores principales: Kiener, Sarah, Kehl, Alexandra, Loechel, Robert, Langbein-Detsch, Ines, Müller, Elisabeth, Bannasch, Danika, Jagannathan, Vidhya, Leeb, Tosso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349258/
https://www.ncbi.nlm.nih.gov/pubmed/32526956
http://dx.doi.org/10.3390/genes11060636