How Do Post-Translational Modifications Influence the Pathomechanistic Landscape of Huntington’s Disease? A Comprehensive Review

Huntington’s disease (HD) is an autosomal dominant inherited neurodegenerative disorder characterized by the loss of motor control and cognitive ability, which eventually leads to death. The mutant huntingtin protein (HTT) exhibits an expansion of a polyglutamine repeat. The mechanism of pathogenesi...

Descripción completa

Detalles Bibliográficos
Autores principales: Lontay, Beata, Kiss, Andrea, Virág, László, Tar, Krisztina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349273/
https://www.ncbi.nlm.nih.gov/pubmed/32560122
http://dx.doi.org/10.3390/ijms21124282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349273/
https://www.ncbi.nlm.nih.gov/pubmed/32560122
http://dx.doi.org/10.3390/ijms21124282

Ejemplares similares