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Comprehensive Analysis of the Immune and Stromal Compartments of the CNS in EAE Mice Reveal Pathways by Which Chloroquine Suppresses Neuroinflammation

Multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE) are neuroinflammatory diseases of the central nervous system (CNS), where leukocytes and CNS resident cells play important roles in disease development and pathogenesis. The antimalarial drug chloroquine (CQ) has been shown...

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Detalles Bibliográficos
Autores principales: Thome, Rodolfo, Boehm, Alexandra, Ishikawa, Larissa Lumi Watanabe, Casella, Giacomo, Munhoz, Jaqueline, Ciric, Bogoljub, Zhang, Guang-Xian, Rostami, Abdolmohamad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349328/
https://www.ncbi.nlm.nih.gov/pubmed/32516999
http://dx.doi.org/10.3390/brainsci10060348