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Comprehensive Analysis of the Immune and Stromal Compartments of the CNS in EAE Mice Reveal Pathways by Which Chloroquine Suppresses Neuroinflammation
Multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE) are neuroinflammatory diseases of the central nervous system (CNS), where leukocytes and CNS resident cells play important roles in disease development and pathogenesis. The antimalarial drug chloroquine (CQ) has been shown...
Autores principales: | Thome, Rodolfo, Boehm, Alexandra, Ishikawa, Larissa Lumi Watanabe, Casella, Giacomo, Munhoz, Jaqueline, Ciric, Bogoljub, Zhang, Guang-Xian, Rostami, Abdolmohamad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349328/ https://www.ncbi.nlm.nih.gov/pubmed/32516999 http://dx.doi.org/10.3390/brainsci10060348 |
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