Top Notch Targeting Strategies in Cancer: A Detailed Overview of Recent Insights and Current Perspectives

Evolutionarily conserved Notch plays a critical role in embryonic development and cellular self-renewal. It has both tumour suppressor and oncogenic activity, the latter of which is widely described. Notch-activating mutations are associated with haematological malignancies and several solid tumours...

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Detalles Bibliográficos
Autores principales: Moore, Gillian, Annett, Stephanie, McClements, Lana, Robson, Tracy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349363/
https://www.ncbi.nlm.nih.gov/pubmed/32575680
http://dx.doi.org/10.3390/cells9061503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349363/
https://www.ncbi.nlm.nih.gov/pubmed/32575680
http://dx.doi.org/10.3390/cells9061503

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