Cargando…
Top Notch Targeting Strategies in Cancer: A Detailed Overview of Recent Insights and Current Perspectives
Evolutionarily conserved Notch plays a critical role in embryonic development and cellular self-renewal. It has both tumour suppressor and oncogenic activity, the latter of which is widely described. Notch-activating mutations are associated with haematological malignancies and several solid tumours...
Autores principales: | Moore, Gillian, Annett, Stephanie, McClements, Lana, Robson, Tracy |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349363/ https://www.ncbi.nlm.nih.gov/pubmed/32575680 http://dx.doi.org/10.3390/cells9061503 |
Ejemplares similares
-
Obesity and Cancer Metastasis: Molecular and Translational Perspectives
por: Annett, Stephanie, et al.
Publicado: (2020) -
FKBPL and its peptide derivatives inhibit endocrine therapy resistant cancer stem cells and breast cancer metastasis by downregulating DLL4 and Notch4
por: McClements, Lana, et al.
Publicado: (2019) -
Prognostic Significance of Glucocorticoid Receptor Expression in Cancer: A Systematic Review and Meta-Analysis
por: Bakour, Noor, et al.
Publicado: (2021) -
Top notch /
por: Saslow, Joan M.
Publicado: (2011) -
Recent Advances in the Gastrointestinal Fate of Organic and Inorganic Nanoparticles in Foods
por: Zhou, Hualu, et al.
Publicado: (2022)