Evaluation of the CRISPR/Cas9 Genetic Constructs in Efficient Disruption of Porcine Genes for Xenotransplantation Purposes Along with an Assessment of the Off-Target Mutation Formation

The increasing life expectancy of humans has led to an increase in the number of patients with chronic diseases and organ failure. However, the imbalance between the supply and the demand for human organs is a serious problem in modern transplantology. One of many solutions to overcome this problem...

Descripción completa

Detalles Bibliográficos
Autores principales: Ryczek, Natalia, Hryhorowicz, Magdalena, Lipiński, Daniel, Zeyland, Joanna, Słomski, Ryszard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349392/
https://www.ncbi.nlm.nih.gov/pubmed/32604937
http://dx.doi.org/10.3390/genes11060713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349392/
https://www.ncbi.nlm.nih.gov/pubmed/32604937
http://dx.doi.org/10.3390/genes11060713

Ejemplares similares