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Oxidative Stress Induces a VEGF Autocrine Loop in the Retina: Relevance for Diabetic Retinopathy

Background: Oxidative stress (OS) plays a central role in diabetic retinopathy (DR), triggering expression and release of vascular endothelial growth factor (VEGF), the increase of which leads to deleterious vascular changes. We tested the hypothesis that OS-stimulated VEGF induces its own expressio...

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Detalles Bibliográficos
Autores principales: Rossino, Maria Grazia, Lulli, Matteo, Amato, Rosario, Cammalleri, Maurizio, Dal Monte, Massimo, Casini, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349409/
https://www.ncbi.nlm.nih.gov/pubmed/32545222
http://dx.doi.org/10.3390/cells9061452