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The Changes of Expression and Methylation of Genes Involved in Oxidative Stress in Course of Chronic Mild Stress and Antidepressant Therapy with Agomelatine

Preclinical studies conducted so far suggest that oxidative stress processes may be associated with the mechanism of depression development. This study shows the effects of chronic administration of agomelatine on expression and the methylation status of Sod1, Sod2, Gpx1, Gpx4, Cat, Nos1, and Nos2 i...

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Detalles Bibliográficos
Autores principales: Wigner, Paulina, Synowiec, Ewelina, Jóźwiak, Paweł, Czarny, Piotr, Bijak, Michał, Barszczewska, Gabriela, Białek, Katarzyna, Szemraj, Janusz, Gruca, Piotr, Papp, Mariusz, Śliwiński, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349414/
https://www.ncbi.nlm.nih.gov/pubmed/32545212
http://dx.doi.org/10.3390/genes11060644