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MicroRNA-19a Targets Fibroblast Growth Factor-Inducible Molecule 14 and Prevents Tubular Damage in Septic AKI

Fibroblast growth factor-inducible molecule 14 (Fn14) plays a principal role in triggering tubular damage during septic acute kidney injury (AKI). Here, we explore the mechanism underlying Fn14 deregulation in septic AKI. We identify Fn14 as a bona fide target of miR-19a, which directly binds to 3′...

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Detalles Bibliográficos
Autores principales: Hong, Jun, Hu, Bang-Chuan, Xu, Liang, Zheng, Yang, Shao, Zi-Qiang, Zhang, Run, Yang, Xiang-Hong, Sun, Ren-Hua, Mo, Shi-Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349421/
https://www.ncbi.nlm.nih.gov/pubmed/32670778
http://dx.doi.org/10.1155/2020/2894650