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Macrophage, the potential key mediator in CAR-T related CRS

Chimeric antigen receptor (CAR) T cell therapy is a new frontier in cancer therapy. The toxicity of cytokine release syndrome (CRS) has become one of the major challenges that limits the wider use of CAR T cells to fight cancer. Exploration of CRS pathogenesis and treatment is becoming the main focu...

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Detalles Bibliográficos
Autores principales: Hao, Zhaonian, Li, Ruyuan, Meng, Li, Han, Zhiqiang, Hong, Zhenya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349474/
https://www.ncbi.nlm.nih.gov/pubmed/32665874
http://dx.doi.org/10.1186/s40164-020-00171-5