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Using Next Generation Sequencing to Study the Genetic Diversity of Candidate Live Attenuated Zika Vaccines

Zika virus (ZIKV) is a mosquito-transmitted positive-sense RNA virus in the family Flaviviridae. Candidate live-attenuated vaccine (LAV) viruses with engineered deletions in the 3’ untranslated region (UTR) provide immunity and protection in animal models of ZIKV infection, and phenotypic studies sh...

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Detalles Bibliográficos
Autores principales: Collins, Natalie D., Shan, Chao, Nunes, Bruno T.D., Widen, Steven G., Shi, Pei-Yong, Barrett, Alan D.T., Sarathy, Vanessa V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349499/
https://www.ncbi.nlm.nih.gov/pubmed/32260110
http://dx.doi.org/10.3390/vaccines8020161