Sildenafil Recovers Burn-Induced Cardiomyopathy

Background: Severe burn injury initiates a feedback cycle of inflammation, fibrosis, oxidative stress and cardiac mitochondrial damage via the PDE5A-cGMP-PKG pathway. Aim: To test if the PDE5A-cGMP-PKG pathway may contribute to burn-induced heart dysfunction. Methods: Sprague–Dawley rats were divide...

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Detalles Bibliográficos
Autores principales: Wen, Jake J., Cummins, Claire, Radhakrishnan, Ravi S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349507/
https://www.ncbi.nlm.nih.gov/pubmed/32503314
http://dx.doi.org/10.3390/cells9061393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349507/
https://www.ncbi.nlm.nih.gov/pubmed/32503314
http://dx.doi.org/10.3390/cells9061393

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