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In Matrix Derivatization Combined with LC-MS/MS Results in Ultrasensitive Quantification of Plasma Free Metanephrines and Catecholamines

[Image: see text] Plasma-free metanephrines and catecholamines are essential markers in the biochemical diagnosis and follow-up of neuroendocrine tumors and inborn errors of metabolism. However, their low circulating concentrations (in the nanomolar range) and poor fragmentation characteristics hind...

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Detalles Bibliográficos
Autores principales: van Faassen, Martijn, Bischoff, Rainer, Eijkelenkamp, Karin, de Jong, Wilhelmina H. A., van der Ley, Claude P., Kema, Ido P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349590/
https://www.ncbi.nlm.nih.gov/pubmed/32484659
http://dx.doi.org/10.1021/acs.analchem.0c01263