Preimplantation Genetic Testing for Polygenic Disease Relative Risk Reduction: Evaluation of Genomic Index Performance in 11,883 Adult Sibling Pairs

Preimplantation genetic testing for polygenic disease risk (PGT-P) represents a new tool to aid in embryo selection. Previous studies demonstrated the ability to obtain necessary genotypes in the embryo with accuracy equivalent to in adults. When applied to select adult siblings with known type I di...

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Detalles Bibliográficos
Autores principales: Treff, Nathan R., Eccles, Jennifer, Marin, Diego, Messick, Edward, Lello, Louis, Gerber, Jessalyn, Xu, Jia, Tellier, Laurent C.A.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349610/
https://www.ncbi.nlm.nih.gov/pubmed/32545548
http://dx.doi.org/10.3390/genes11060648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349610/
https://www.ncbi.nlm.nih.gov/pubmed/32545548
http://dx.doi.org/10.3390/genes11060648

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