Evolution of the T-Cell Receptor (TR) Loci in the Adaptive Immune Response: The Tale of the TRG Locus in Mammals

T lymphocytes are the principal actors of vertebrates’ cell-mediated immunity. Like B cells, they can recognize an unlimited number of foreign molecules through their antigen-specific heterodimer receptors (TRs), which consist of αβ or γδ chains. The diversity of the TRs is mainly due to the unique...

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Detalles Bibliográficos
Autores principales: Antonacci, Rachele, Massari, Serafina, Linguiti, Giovanna, Caputi Jambrenghi, Anna, Giannico, Francesco, Lefranc, Marie-Paule, Ciccarese, Salvatrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349638/
https://www.ncbi.nlm.nih.gov/pubmed/32517024
http://dx.doi.org/10.3390/genes11060624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349638/
https://www.ncbi.nlm.nih.gov/pubmed/32517024
http://dx.doi.org/10.3390/genes11060624

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