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Conditionally Reprogrammed Cells from Patient-Derived Xenograft to Model Neuroendocrine Prostate Cancer Development

Neuroendocrine prostate cancer (NEPC) is a lethal subtype of prostate cancer. It develops mainly via NE transdifferentiation of prostate adenocarcinoma in response to androgen receptor (AR)-inhibition therapy. The study of NEPC development has been hampered by a lack of clinically relevant models. W...

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Detalles Bibliográficos
Autores principales: Ci, Xinpei, Hao, Jun, Dong, Xin, Xue, Hui, Wu, Rebecca, Choi, Stephen Yiu Chuen, Haegert, Anne M., Collins, Colin C., Liu, Xuefeng, Lin, Dong, Wang, Yuzhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349646/
https://www.ncbi.nlm.nih.gov/pubmed/32512818
http://dx.doi.org/10.3390/cells9061398