Human Nasal Epithelial Organoids for Therapeutic Development in Cystic Fibrosis

We describe a human nasal epithelial (HNE) organoid model derived directly from patient samples that is well-differentiated and recapitulates the airway epithelium, including the expression of cilia, mucins, tight junctions, the cystic fibrosis transmembrane conductance regulator (CFTR), and ionocyt...

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Detalles Bibliográficos
Autores principales: Liu, Zhongyu, Anderson, Justin D., Deng, Lily, Mackay, Stephen, Bailey, Johnathan, Kersh, Latona, Rowe, Steven M., Guimbellot, Jennifer S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349680/
https://www.ncbi.nlm.nih.gov/pubmed/32485957
http://dx.doi.org/10.3390/genes11060603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349680/
https://www.ncbi.nlm.nih.gov/pubmed/32485957
http://dx.doi.org/10.3390/genes11060603

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