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TERC Variants Associated with Short Leukocyte Telomeres: Implication of Higher Early Life Leukocyte Telomere Attrition as Assessed by the Blood-and-Muscle Model

Short leukocyte telomere length (LTL) is associated with atherosclerotic cardiovascular disease (ASCVD). Mendelian randomisation studies, using single nucleotide polymorphisms (SNPs) associated with short LTL, infer a causal role of LTL in ASCVD. Recent results, using the blood-and-muscle model, ind...

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Detalles Bibliográficos
Autores principales: Toupance, Simon, Stathopoulou, Maria G., Petrelis, Alexandros M., Gorenjak, Vesna, Labat, Carlos, Lai, Tsung-Po, Visvikis-Siest, Sophie, Benetos, Athanase
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349705/
https://www.ncbi.nlm.nih.gov/pubmed/32486379
http://dx.doi.org/10.3390/cells9061360