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Role of 2-Arachidonoyl-Glycerol and CB1 Receptors in Orexin-A-Mediated Prevention of Oxygen–Glucose Deprivation-Induced Neuronal Injury

Orexin-A (OX-A) protects the brain against oxidative stress-mediated ischemic injury. Since the endocannabinoid 2-arachidonoylglycerol (2-AG) and cannabinoid type-1 (CB1) receptors were previously shown to mediate some of the effects of OX-A exerted through the orexin-1 receptor (OX-1R), we investig...

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Detalles Bibliográficos
Autores principales: Palomba, Letizia, Motta, Andrea, Imperatore, Roberta, Piscitelli, Fabiana, Capasso, Raffaele, Mastroiacovo, Federica, Battaglia, Giuseppe, Bruno, Valeria, Cristino, Luigia, Di Marzo, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349736/
https://www.ncbi.nlm.nih.gov/pubmed/32575773
http://dx.doi.org/10.3390/cells9061507