Cargando…

Maternal Tryptophan Supplementation Protects Adult Rat Offspring against Hypertension Programmed by Maternal Chronic Kidney Disease: Implication of Tryptophan-Metabolizing Microbiome and Aryl Hydrocarbon Receptor

Hypertension and chronic kidney disease (CKD) can originate during early-life. Tryptophan metabolites generated by different pathways have both detrimental and beneficial effects. In CKD, uremic toxins from the tryptophan-generating metabolites are endogenous ligands of the aryl hydrocarbon receptor...

Descripción completa

Detalles Bibliográficos
Autores principales: Hsu, Chien-Ning, Lin, I-Chun, Yu, Hong-Ren, Huang, Li-Tung, Tiao, Mao-Meng, Tain, You-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349830/
https://www.ncbi.nlm.nih.gov/pubmed/32604820
http://dx.doi.org/10.3390/ijms21124552