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Maternal Tryptophan Supplementation Protects Adult Rat Offspring against Hypertension Programmed by Maternal Chronic Kidney Disease: Implication of Tryptophan-Metabolizing Microbiome and Aryl Hydrocarbon Receptor
Hypertension and chronic kidney disease (CKD) can originate during early-life. Tryptophan metabolites generated by different pathways have both detrimental and beneficial effects. In CKD, uremic toxins from the tryptophan-generating metabolites are endogenous ligands of the aryl hydrocarbon receptor...
Autores principales: | Hsu, Chien-Ning, Lin, I-Chun, Yu, Hong-Ren, Huang, Li-Tung, Tiao, Mao-Meng, Tain, You-Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349830/ https://www.ncbi.nlm.nih.gov/pubmed/32604820 http://dx.doi.org/10.3390/ijms21124552 |
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