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Preclinical Efficacy of a Trivalent Human FcγRI-Targeted Adjuvant-Free Subunit Mucosal Vaccine against Pulmonary Pneumococcal Infection

Lack of safe and effective mucosal adjuvants has severely hampered the development of mucosal subunit vaccines. In this regard, we have previously shown that immunogenicity of vaccine antigens can be improved by targeting the antigens to the antigen-presenting cells. Specifically, groups of mice imm...

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Detalles Bibliográficos
Autores principales: Kumar, Sudeep, Sunagar, Raju, Gosselin, Edmund J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349865/
https://www.ncbi.nlm.nih.gov/pubmed/32340134
http://dx.doi.org/10.3390/vaccines8020193