High Content Screening Using New U2OS Reporter Cell Models Identifies Harmol Hydrochloride as a Selective and Competitive Antagonist of the Androgen Receptor

Prostate cancer is the most commonly diagnosed malignancy in men. Its growth mainly relies on the activity of the androgen receptor (AR), justifying the use of androgen deprivation therapy as a gold standard treatment for the metastatic disease. Inhibition of the androgen axis using second generatio...

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Detalles Bibliográficos
Autores principales: Dellal, Hadjer, Boulahtouf, Abdelhay, Alaterre, Elina, Cuenant, Alice, Grimaldi, Marina, Bourguet, William, Gongora, Céline, Balaguer, Patrick, Pourquier, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349874/
https://www.ncbi.nlm.nih.gov/pubmed/32560058
http://dx.doi.org/10.3390/cells9061469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349874/
https://www.ncbi.nlm.nih.gov/pubmed/32560058
http://dx.doi.org/10.3390/cells9061469

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