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Herpes Simplex Viruses Whose Replication Can Be Deliberately Controlled as Candidate Vaccines

Over the last few years, we have been evaluating a novel paradigm for immunization using viruses or virus-based vectors. Safety is provided not by attenuation or inactivation of vaccine viruses, but by the introduction into the viral genomes of genetic mechanisms that allow for stringent, deliberate...

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Detalles Bibliográficos
Autores principales: Voellmy, Richard, Bloom, David C, Vilaboa, Nuria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349925/
https://www.ncbi.nlm.nih.gov/pubmed/32443425
http://dx.doi.org/10.3390/vaccines8020230