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A Nanoparticle-Poly(I:C) Combination Adjuvant Enhances the Breadth of the Immune Response to Inactivated Influenza Virus Vaccine in Pigs

Intranasal vaccination elicits secretory IgA (SIgA) antibodies in the airways, which is required for cross-protection against influenza. To enhance the breadth of immunity induced by a killed swine influenza virus antigen (KAg) or conserved T cell and B cell peptides, we adsorbed the antigens togeth...

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Detalles Bibliográficos
Autores principales: Renu, Sankar, Feliciano-Ruiz, Ninoshkaly, Lu, Fangjia, Ghimire, Shristi, Han, Yi, Schrock, Jennifer, Dhakal, Santosh, Patil, Veerupaxagouda, Krakowka, Steven, HogenEsch, Harm, Renukaradhya, Gourapura J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349929/
https://www.ncbi.nlm.nih.gov/pubmed/32443416
http://dx.doi.org/10.3390/vaccines8020229