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Modified Alphavirus-Vesiculovirus Hybrid Vaccine Vectors for Homologous Prime-Boost Immunotherapy of Chronic Hepatitis B

Virus-like vesicles (VLV) are hybrid vectors based on an evolved Semliki Forest virus (SFV) RNA replicon and the envelope glycoprotein (G) from vesicular stomatitis virus (VSV). Previously, we showed that VLV can be used to express protein antigens and generate protective antigen-specific CD8(+) T c...

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Detalles Bibliográficos
Autores principales: Chiale, Carolina, Yarovinsky, Timur O., Mason, Stephen W., Madina, Bhaskara R., Menon, Manisha, Krady, Marie M., Moshkani, Safiehkhatoon, Chattopadhyay Pal, Anasuya, Almassian, Bijan, Rose, John K., Robek, Michael D., Nakaar, Valerian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349932/
https://www.ncbi.nlm.nih.gov/pubmed/32517032
http://dx.doi.org/10.3390/vaccines8020279