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N-terminus of Flagellin Fused to an Antigen Improves Vaccine Efficacy against Pasteurella Multocida Infection in Chickens

Flagellin from bacteria elicits a proinflammatory immune response and may act as a vaccine adjuvant. In this study, we evaluated the adjuvant effect of the N-terminus of flagellin (residues 1–99) when linked to an antigen (a truncated, conserved domain of lipoprotein E of Pasteurella multocida). Imm...

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Detalles Bibliográficos
Autores principales: Doan, Thu-Dung, Wang, Hsian-Yu, Ke, Guan-Ming, Cheng, Li-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349934/
https://www.ncbi.nlm.nih.gov/pubmed/32517250
http://dx.doi.org/10.3390/vaccines8020283